DNA Vectors
Vector Biolabs FK506 binding protein 1B, 12.6 kDa Adenovirus (Ad-FKBP1B)
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A.
BIOHIPPO AAV-hSyn-DO-eNpHR3.0-EGFP-WPRE-hGH-polyA
Recombinant adeno associated virus expressing eNpHR3.0 fused to EGFP under the hSyn promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
IBA LifeSciences StrGate Acptr Vctr pCSG-IBA103
pCSG-IBA103 is a large expression vector with universal features for transient expression of target proteins with a C-terminal Twin-Strep-tag as well as for generation of stable mammalian cell lines. The vector carries an ampicillin resistance cassette for selection of transformed E. coli cells and ColE1 origin for a high plasmid copy number. Extrachromosomal replication in mammalian cells could occur either by origin of replication from Epstein-Barr Virus (oriP) or by SV40 ori. For the former the vector provides the EBNA-1 gene and for the latter the cell line has to be latently infected with SV40 or express the SV40 large T antigen (e.g. HEK293T, COS-1, COS-7). Stable cell lines can be selected by the neomycin resistance gene (NeoR). In addition, the human cytomegalovirus (CMV) immediate-early promoter enables a high-level expression in a wide range of mammalian cells.
BIOHIPPO AAV-ChAT-DIO-hM3D(Gq)-mCherry-WPREs
Recombinant adeno associated virus expressing hM3D(Gq) fused to mCherry under the ChAT promoter with WPRE and hGH polyA elements. The Cre and Dre logic configuration enables expression only after recombination, providing precise chemogenetic control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
Vector Biolabs Cre Recombinase Adenovirus (Ad-CMV-iCre)
This Cre recombinant adenovirus expresses Cre recombinase, a Type I topoisomerase from P1 bacteriophage that catalyzes site-specific recombination of DNA between loxP sites. loxP is a 34 bp DNA sequence at which confers directionality. Cre recombinase is used as a tool to genetically modify genes, such as to delete a segment of DNA flanked by LoxP sites in cultured cells or experimental animals.This adenovirus expresses a codon improved Cre (iCre) under a CMV promoter.
Check out this instruction video on using our adenovirus Cre to knockout LoxP flanked gene in primary mouse embryonic fibroblasts (MEF).
Vector Biolabs AAV9 CMV-Null AAV (AAV9-Null)
This AAV serotype 9 virus (with Capsid from AAV9 and ITR from AAV2) has a CMV promoter with no transgene. It's used as control AAV.
Vector Biolabs AAV6-CMV-Null AAV (AAV6 Null)
This AAV serotype 6 virus (with Capsid from AAV6 and ITR from AAV2) has a CMV promoter with no transgene. It's used as control AAV.
Vector Biolabs AAV-CMV-GFP (AAV serotype 8-DJ) AAV (AAV8/DJ-eGFP)
This AAV-DJ8 virus expresses eGFP under a CMV promoter.
BIOHIPPO AAV-CaMKIIa-DIO-DTA-2A-EGFP-WPRE-hGH聽-polyA
Recombinant adeno associated virus expressing DTA fused to EGFP under the CaMKIIa promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.